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Rabbit Anti-FLJ36180 antibody (bs-16126R)
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说明书:100ul  200ul
100ul/1380.00元
200ul/2200.00元
大包装/询价
产品编号bs-16126R
英文名称FLJ36180
中文名称RNF209/环指蛋白209抗体
别    名EC 6.3.2.-; FLJ36180; MGC138638; MGC138639; Probable E3 ubiquitin-protein ligase TRIML1; RING finger protein 209; RNF209; TRIML_HUMAN; Triml1; Tripartite motif family like protein 1; Tripartite motif family-like protein 1.  
规格价格100ul/1380元购买    200ul/2200元购买    大包装/询价
说 明 书100ul  200ul
研究领域细胞生物  免疫学  转录调节因子  表观遗传学  环指蛋白  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
性    状Lyophilized or Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human FLJ36180:/351-450/468 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation.TRIML1 (tripartite motif family-like 1), also known as RNF209 (RING finger protein 209), is a 468 amino acid protein that contains one SPRY domain and one RING-type zinc finger. Due to the presence of a RING-type zinc finger motif, TRIML1 may be involved in protein degradation events within the cell.

Function:
Probable E3 ubiquitin-protein ligase which plays an important role in blastocyst development.

Subunit:
Interacts with USP5 (By similarity).

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

SWISS:
Q8N9V2

Gene ID:
339976

Database links:

Entrez Gene: 339976 Human

Entrez Gene: 244448 Mouse

SwissProt: Q8N9V2 Human

SwissProt: Q8BVP1 Mouse

Unigene: 348618 Human

Unigene: 64542 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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